IVF has higher risk of complications and multiple births

June 8, 2012 18:12 by PrideAngelAdmin
multiple births A recent report states that there is a higher risk of complications and multiple births in pregnancies that result from IVF techniques.

A report by the Royal College of Obstetricians and Gynaecologists said there were increased risks of premature births, low birth weight and congenital abnormalities. However, it said the vast majority of IVF children were as healthy as other children. IVF accounts for over 1% of UK births. Advances in fertility research have allowed more infertile couples to have children and at an older age.

Risks

The Royal College's Scientific Advisory Committee reviewed the risks of IVF, which it said were directly related to the number of foetuses and that IVF techniques appeared to double the risk of twins.

It said: "About one in four of all IVF pregnancies result in a multiple birth in the UK owing to the common practice of replacing two or three embryos."

It also said there was a 23% increased risk of a premature birth, but the risk remained low. "IVF pregnancies still demonstrate an increased risk of low birth weight," it said. Heart defects, cleft lips and other congenital anomalies are also more common. It said around 5% of all babies were diagnosed with an abnormality, but IVF babies were around a third more likely to have a problem.

Long term

Later in life, the report said there were no differences in brain, language or behavioural development and there "appears to be little impact at age 12".

Prof Jenny Kurinczuk, director of the National Perinatal Epidemiology Unit at the University of Oxford, said: "IVF pregnancies carry an increased risk of poor birth outcomes and complications. Nevertheless the majority of the children born following IVF will have a good outcome just like any other children.

"The poor birth outcomes and complications may be a combination of treatment and underlying features of the couple such as older maternal age. However, treatment strategies can be altered to improve outcomes such as the adoption of elective single embryo transfer."

Read more about alternatives to IVF such as home insemination and the Duo-fertility monitor which is as effective as one cycle of IVF after 6 months of use.

Article: 6th June www.bbc.co.uk

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More twins being born due to fertility treatments and older mothers

January 4, 2012 20:10 by PrideAngelAdmin
twin babies More U.S. women are having twins these days. The reason? Older moms and fertility treatments. One in every 30 babies born in the U.S. is a twin — an astounding increase over the last three decades, according to a government report issued Wednesday. In 1980, only 1 in every 53 babies was a twin.

“When people say it seems like you see more twins nowadays, they’re right,” said Joyce Martin, an epidemiologist who co-authored the Centers for Disease Control and Prevention report.

Some increase was expected as more women are waiting until they are over 30 to have babies. For some unknown reason, mothers in their 30s are more likely to have twins than younger or older women. As much as a third of the increase can be attributed to that, Martin said.

The rest of the rise is due to fertility drugs and treatments, experts said. “You have a double whammy going on. There are more older moms and more widespread use of fertility-enhancing therapies,” Martin said.

Starting in the early 1980s, couples who had trouble conceiving began to benefit from medical advances like fertility drugs and in vitro fertilization and other procedures. These treatments became fairly widespread in the 1990s but are expensive, and availability and insurance coverage varies.

The twin birth rate rose by more than 2 percent a year, on average, from 1980 through 2004. It leveled off to less than 1 percent annually although the rise from 2008 to 2009 was nearly 2 percent.

In 2009, twin rates increased in all 50 states, though the jumps were highest in lower New England, New Jersey and Hawaii. In Connecticut, twins now account for nearly 5 percent of births. That’s high. Nationally, 3.3 percent of all births were twins in 2009, up from 2 percent in 1980.

Over the last three decades, rates rose for white, black and Hispanic women, but the increases were not uniform. Rates doubled for whites, rose by half for blacks and by about a third for Hispanics. Historically, black moms have twins most often, but white moms have almost caught up.

“That’s changed with infertility treatments,” said Barbara Luke, a Michigan State University expert on twin births. The greatest increase in twin rates was for women 40 and older. They are more likely to use fertility treatments and to have two embryos implanted during in vitro fertilization, whereas younger women are more likely to get just one.

About 7 percent of all births for women 40 and older were twins, compared to 5 percent of women in their late 30s and 2 percent of women age 24 or younger.

While a lot of attention is focused on the impact of fertility treatments, that’s not the only factor. Before fertility treatments existed, about 2.5 percent of the babies born to women in their late 30s were twins, compared to under 2 percent for younger and older women. Some research has suggested women in that age group are more likely to produce multiple eggs in a cycle, increasing their chances of twins.

Clearly, there are more older moms. In recent years, more than a third of all births are to women 30 and older, up from just one-fifth in 1980.

Are more twins good news? Some experts say the trend is worrisome, noting that multiple births are more dangerous for the mother and their babies. The infants tend to be born earlier, smaller and weaker, and require much more care.

But for some older women worried about conceiving, “having twins is a blessing,” Luke said.

Article: 4th January 2012 www.washingtonpost.com

Trying to get pregnant quick? read here for alternatives to IVF.

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Multiple embryo transfers during IVF are reducing says HFEA

June 2, 2011 17:49 by PrideAngelAdmin
The proportion of risky multiple births during IVF treatment is falling according to the Human Fertilisation and Embryology Authority (HFEA). Multiple birth pregnancies have a higher chance of miscarriage, and of leading to premature birth and of babies with cerebral palsy.

The HFEA said 23.6% of IVF births led to more than one child at the beginning of 2008, which fell to 22% in mid 2009. The Multiple Births Foundation said it was "great news".

Multiple births are a consequence of increasing the odds of IVF working. Implanting more embryos increases the chance of success, but also the chance of twins or triplets. The HFEA has introduced targets for reducing multiple births because of the health concerns for mother and child. It has aimed for fewer than 24% IVF births resulting in more than one child by April 2010, 20% by April 2011 and 15% by April 2012.

Multiple births have health risks for the babies and the mother. The reduction so far has largely been down to increased use of a technique called single embryo transfer. Only one embryo is implanted in women who have the greatest chance of getting pregnant. HFEA figures show this has not affected the success rate.

Professor Lisa Jardine, chair of the HFEA said: "It is excellent news that the number of multiple births is coming down whilst overall success rates for patients are still being maintained. This shows that the policy is proving successful." Susan Seenan, from the Infertility Network UK, said: "With full funding on the NHS - if patients could access three cycles - a lot more women would be willing and able to go for single embryo transfer.

"Some women who are only getting one cycle feel they are limiting their chances of success." Jane Denton, director of the Multiple Births Foundation said: "There is no doubt that a multiple pregnancy creates risks for both mother and babies. The good news is that the strategy is working."

Article: May 2011 www.bbc.co.uk

Read more about IVF, sperm donation and gay parenting at www.prideangel.com

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